A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family

The propensity for differentiation varies substantially across human pluripotent stem cell (hPSC) lines, greatly restricting the use of hPSCs for cell replacement therapy or disease modeling. Here, we investigate the underlying mechanisms and demonstrate that activation of the retinoblastoma (Rb) pa...

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Detalles Bibliográficos
Autores principales: Li, Jingling, Narayanan, Cyndhavi, Bian, Jing, Sambo, Danielle, Brickler, Thomas, Zhang, Wancong, Chetty, Sundari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291069/
https://www.ncbi.nlm.nih.gov/pubmed/30540809
http://dx.doi.org/10.1371/journal.pone.0208110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291069/
https://www.ncbi.nlm.nih.gov/pubmed/30540809
http://dx.doi.org/10.1371/journal.pone.0208110

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