Cargando…

A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family

The propensity for differentiation varies substantially across human pluripotent stem cell (hPSC) lines, greatly restricting the use of hPSCs for cell replacement therapy or disease modeling. Here, we investigate the underlying mechanisms and demonstrate that activation of the retinoblastoma (Rb) pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jingling, Narayanan, Cyndhavi, Bian, Jing, Sambo, Danielle, Brickler, Thomas, Zhang, Wancong, Chetty, Sundari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291069/ https://www.ncbi.nlm.nih.gov/pubmed/30540809 http://dx.doi.org/10.1371/journal.pone.0208110

Ejemplares similares

Brief Report: Cell Cycle Dynamics of Human Pluripotent Stem Cells Primed for Differentiation
por: Shcherbina, Anna, et al.
Publicado: (2019)

A simple tool to improve pluripotent stem cell differentiation
por: Chetty, Sundari, et al.
Publicado: (2013)

Effects of DMSO on the Pluripotency of Cultured Mouse Embryonic Stem Cells (mESCs)
por: Sousa, Maria Inês, et al.
Publicado: (2020)

DMSO-Free Programmed Cryopreservation of Fully Dissociated and Adherent Human Induced Pluripotent Stem Cells
por: Katkov, Igor I., et al.
Publicado: (2011)

DMSO Efficiently Down Regulates Pluripotency Genes in Human Embryonic Stem Cells during Definitive Endoderm Derivation and Increases the Proficiency of Hepatic Differentiation
por: Czysz, Katherine, et al.
Publicado: (2015)

A Src inhibitor regulates the cell cycle of human pluripotent stem cells and improves directed differentiation
por: Chetty, Sundari, et al.
Publicado: (2015)

An improved ScoreCard to assess the differentiation potential of human pluripotent stem cells
por: Tsankov, Alexander M., et al.
Publicado: (2015)

DMSO Reductase Family: Phylogenetics and Applications of Extremophiles
por: Miralles-Robledillo, Jose María, et al.
Publicado: (2019)

Methane, arsenic, selenium and the origins of the DMSO reductase family
por: Wells, Michael, et al.
Publicado: (2020)

Microwave Sensor for the Determination of DMSO Concentration in Water–DMSO Binary Mixture
por: Harnsoongnoen, Supakorn, et al.
Publicado: (2023)

p130 And pRb in the Maintenance of Transient Quiescence of Mesenchymal Stem Cells
por: Popov, Boris, et al.
Publicado: (2020)

Low DMSO Cryopreservation of Stem Cells Enabled by Macromolecular Cryoprotectants
por: Murray, Kathryn A., et al.
Publicado: (2020)

First Iridium(IV) Chloride–Dimethyl Sulfoxide Complex [H(dmso)(2)][IrCl(5)(dmso-κO)]: Synthesis and Structure along with Novel Polymorph Modifications of [H(dmso)(2)][trans-IrCl(4)(dmso-κS)(2)] and [H(dmso)][trans-IrCl(4)(dmso-κS)(2)]
por: Rudnitskaya, Olga V., et al.
Publicado: (2023)

Microstructural free volume and dynamics of cryoprotective DMSO–water mixtures at low DMSO concentration
por: Čechová, Katarína, et al.
Publicado: (2019)

The Persecuted Drug. The Story of DMSO
por: McGuire, Joseph
Publicado: (1975)

Weak Interactions in Dimethyl Sulfoxide (DMSO)–Tertiary Amide Solutions: The Versatility of DMSO as a Solvent
por: Di Mino, Camilla, et al.
Publicado: (2023)

DMSO increases efficiency of genome editing at two non-coding loci
por: Stratigopoulos, George, et al.
Publicado: (2018)

pRB-Depleted Pluripotent Stem Cell Retinal Organoids Recapitulate Cell State Transitions of Retinoblastoma Development and Suggest an Important Role for pRB in Retinal Cell Differentiation
por: Rozanska, Agata, et al.
Publicado: (2022)

Effect of DMSO on lifespan and physiology in C. elegans : Implications for use of DMSO as a solvent for compound delivery
por: AlOkda, Abdelrahman, et al.
Publicado: (2022)

DMSO modulates the pathway of apoptosis triggering
por: Banič, Blaž, et al.
Publicado: (2011)

Increased Crystallization of CuTCNQ in Water/DMSO Bisolvent for Enhanced Redox Catalysis
por: Hussain, Zakir, et al.
Publicado: (2021)

Hydrogenation of CO(2) to Formic Acid with a Highly Active Ruthenium Acriphos Complex in DMSO and DMSO/Water
por: Rohmann, Kai, et al.
Publicado: (2016)

Dissolution of Cellulose in Ionic Liquid–DMSO Mixtures: Roles of DMSO/IL Ratio and the Cation Alkyl Chain Length
por: Ren, Fei, et al.
Publicado: (2021)

DMSO Solubility Assessment for Fragment-Based Screening
por: Baybekov, Shamkhal, et al.
Publicado: (2021)

Solubility of Hybrid Halide Perovskites in DMF and DMSO
por: Petrov, Andrey A., et al.
Publicado: (2021)

Oxaliplatin reacts with DMSO only in the presence of water
por: Varbanov, Hristo P., et al.
Publicado: (2017)

BUDR inhibition of post-DMSO-induced erythroleukaemia cell differentiation in vitro.
por: Preisler, H. D.
Publicado: (1976)

Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells
por: Akiyama, Tomohiko, et al.
Publicado: (2016)

To Rb or not to Rb
por: Wells, William A.
Publicado: (2002)

Complete Genome Sequences of T4-Like Bacteriophages RB3, RB5, RB6, RB7, RB9, RB10, RB27, RB33, RB55, RB59, and RB68
por: Yaung, Stephanie J., et al.
Publicado: (2015)

Synthesis of methylenebisamides using CC- or DCMT-activated DMSO
por: Wang, Qiang, et al.
Publicado: (2008)

Protein Conformation and Supercharging with DMSO from Aqueous Solution
por: Sterling, Harry J., et al.
Publicado: (2011)

On crystallization of water confined in liposomes and cryoprotective action of DMSO
por: Klbik, Ivan, et al.
Publicado: (2022)

Behavior of α, β tubulin in DMSO-containing electrolytes
por: Kalra, Aarat P., et al.
Publicado: (2019)

Lights and Shadows of DMSO as Solvent for Tin Halide Perovskites
por: Pascual, Jorge, et al.
Publicado: (2022)

Recent Advances in DMSO-Based Direct Synthesis of Heterocycles
por: Cui, Hai-Lei
Publicado: (2022)

PCL and DMSO(2) Composites for Bio-Scaffold Materials
por: Jang, Jae-Won, et al.
Publicado: (2023)

Crystal structures of polymerized lithium chloride and dimethyl sulfoxide in the form of {2LiCl·3DMSO}( n ) and {LiCl·DMSO}( n )
por: Valdez, Nichole R., et al.
Publicado: (2023)

Rb and hematopoiesis: stem cells to anemia
por: Walkley, Carl R, et al.
Publicado: (2008)

Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection
por: Steyer, Benjamin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qccin9t2v5029rhtvg3dm7s8v3