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Gamma secretase dependent release of the CD44 cytoplasmic tail upregulates IFI16 in cd44(-/-) tumor cells, MEFs and macrophages

The adhesion molecule and co-receptor of receptor tyrosine kinases, CD44, is expressed in all cells of the immune system, but also in numerous non-immune cells. CD44 plays roles in the cellular response to different pathogens. The molecular actions of CD44 during these processes are by and large sti...

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Detalles Bibliográficos
Autores principales: Schultz, Kristin, Grieger (Lindner), Christina, Li, Yong, Urbánek, Pavel, Ruschel, Anne, Minnich, Kerstin, Bruder, Dunja, Gereke, Marcus, Sechi, Antonio, Herrlich, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291121/
https://www.ncbi.nlm.nih.gov/pubmed/30540779
http://dx.doi.org/10.1371/journal.pone.0207358