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Gamma secretase dependent release of the CD44 cytoplasmic tail upregulates IFI16 in cd44(-/-) tumor cells, MEFs and macrophages
The adhesion molecule and co-receptor of receptor tyrosine kinases, CD44, is expressed in all cells of the immune system, but also in numerous non-immune cells. CD44 plays roles in the cellular response to different pathogens. The molecular actions of CD44 during these processes are by and large sti...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291121/ https://www.ncbi.nlm.nih.gov/pubmed/30540779 http://dx.doi.org/10.1371/journal.pone.0207358 |