Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection

Ym1 and RELMα are established effector molecules closely synonymous with Th2-type inflammation and associated pathology. Here, we show that whilst largely dependent on IL-4Rα signaling during a type 2 response, Ym1 and RELMα also have IL-4Rα-independent expression patterns in the lung. Notably, we f...

Descripción completa

Detalles Bibliográficos
Autores principales: Sutherland, Tara E., Rückerl, Dominik, Logan, Nicola, Duncan, Sheelagh, Wynn, Thomas A., Allen, Judith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291165/
https://www.ncbi.nlm.nih.gov/pubmed/30500858
http://dx.doi.org/10.1371/journal.ppat.1007423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291165/
https://www.ncbi.nlm.nih.gov/pubmed/30500858
http://dx.doi.org/10.1371/journal.ppat.1007423

Ejemplares similares