SOX2 haploinsufficiency promotes impaired vision at advanced age

Age-related vision loss has been associated with degeneration of the retina and decline in Müller glia cell activity. Sox2 is a critical transcription factor for the development and maintenance of the mammalian retina. Here we determined the role of Sox2 in retinal aging. We observed a decline in th...

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Detalles Bibliográficos
Autores principales: Moreno-Cugnon, Leire, Anasagasti, Ander, Ezquerra-Inchausti, Maitane, Izeta, Ander, de la Villa, Pedro, Ruiz-Ederra, Javier, Matheu, Ander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291181/
https://www.ncbi.nlm.nih.gov/pubmed/30613351
http://dx.doi.org/10.18632/oncotarget.26393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291181/
https://www.ncbi.nlm.nih.gov/pubmed/30613351
http://dx.doi.org/10.18632/oncotarget.26393

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