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Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth

Oncogenic lesions are surprisingly common in morphologically and functionally normal human skin, however, the cellular and molecular mechanisms that suppress their cancer-driving potential to maintain tissue homeostasis are unknown. By employing assays for direct and quantitative assessment of cell...

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Detalles Bibliográficos
Autores principales: Ying, Zhe, Sandoval, Madeline, Beronja, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291208/
https://www.ncbi.nlm.nih.gov/pubmed/30361695
http://dx.doi.org/10.1038/s41556-018-0218-9