Cargando…

Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays

Atonal homolog 1 (Atoh1) is a basic helix-loop-helix 9 (bHLH) transcription factor acting downstream of Notch and is required for the differentiation of sensory hair cells in the inner ear and the specification of secretory cells during the intestinal crypt cell regeneration. Motivated by the observ...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Xin, Kirkpatrick, Robert, Hofmann, Glenn, Grillot, Didier, Linhart, Valerie, Viviani, Fabrice, Marino, Joseph, Boyer, Joseph, Graham, Taylor L., Lu, Quinn, Wu, Zining, Benowitz, Andrew, Cousins, Rick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291236/
https://www.ncbi.nlm.nih.gov/pubmed/30540745
http://dx.doi.org/10.1371/journal.pone.0207140