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Macrophage Mineralocorticoid Receptor Is a Pleiotropic Modulator of Myocardial Infarct Healing

Myocardial infarction (MI) is a major cause of death worldwide. Here, we identify the macrophage MR (mineralocorticoid receptor) as a crucial pathogenic player in cardiac wound repair after MI. Seven days after left coronary artery ligation, mice with myeloid cell–restricted MR deficiency compared w...

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Detalles Bibliográficos
Autores principales: Fraccarollo, Daniela, Thomas, Svenja, Scholz, Claus-Jürgen, Hilfiker-Kleiner, Denise, Galuppo, Paolo, Bauersachs, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott, Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291261/
https://www.ncbi.nlm.nih.gov/pubmed/30543467
http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12162