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Macrophage Mineralocorticoid Receptor Is a Pleiotropic Modulator of Myocardial Infarct Healing
Myocardial infarction (MI) is a major cause of death worldwide. Here, we identify the macrophage MR (mineralocorticoid receptor) as a crucial pathogenic player in cardiac wound repair after MI. Seven days after left coronary artery ligation, mice with myeloid cell–restricted MR deficiency compared w...
Autores principales: | Fraccarollo, Daniela, Thomas, Svenja, Scholz, Claus-Jürgen, Hilfiker-Kleiner, Denise, Galuppo, Paolo, Bauersachs, Johann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott, Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291261/ https://www.ncbi.nlm.nih.gov/pubmed/30543467 http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12162 |
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