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New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration

After brain injury, neural stem cell–derived neuronal precursors (neuroblasts) in the ventricular-subventricular zone migrate toward the lesion. However, the ability of the mammalian brain to regenerate neuronal circuits for functional recovery is quite limited. Here, using a mouse model for ischemi...

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Detalles Bibliográficos
Autores principales: Kaneko, N., Herranz-Pérez, V., Otsuka, T., Sano, H., Ohno, N., Omata, T., Nguyen, H. B., Thai, T. Q., Nambu, A., Kawaguchi, Y., García-Verdugo, J. M., Sawamoto, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291311/
https://www.ncbi.nlm.nih.gov/pubmed/30547091
http://dx.doi.org/10.1126/sciadv.aav0618