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New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration
After brain injury, neural stem cell–derived neuronal precursors (neuroblasts) in the ventricular-subventricular zone migrate toward the lesion. However, the ability of the mammalian brain to regenerate neuronal circuits for functional recovery is quite limited. Here, using a mouse model for ischemi...
Autores principales: | Kaneko, N., Herranz-Pérez, V., Otsuka, T., Sano, H., Ohno, N., Omata, T., Nguyen, H. B., Thai, T. Q., Nambu, A., Kawaguchi, Y., García-Verdugo, J. M., Sawamoto, K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291311/ https://www.ncbi.nlm.nih.gov/pubmed/30547091 http://dx.doi.org/10.1126/sciadv.aav0618 |
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