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Neuroinflammatory signals drive spinal curve formation in zebrafish models of idiopathic scoliosis

The etiopathogenesis of idiopathic scoliosis (IS), a highly prevalent spinal deformity that occurs in the absence of obvious congenital or physiological abnormalities, is poorly understood. Although recent zebrafish genetic studies have linked cilia motility and cerebrospinal fluid (CSF) flow defect...

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Detalles Bibliográficos
Autores principales: Van Gennip, J. L. M., Boswell, C. W., Ciruna, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291318/
https://www.ncbi.nlm.nih.gov/pubmed/30547092
http://dx.doi.org/10.1126/sciadv.aav1781