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Neuroinflammatory signals drive spinal curve formation in zebrafish models of idiopathic scoliosis
The etiopathogenesis of idiopathic scoliosis (IS), a highly prevalent spinal deformity that occurs in the absence of obvious congenital or physiological abnormalities, is poorly understood. Although recent zebrafish genetic studies have linked cilia motility and cerebrospinal fluid (CSF) flow defect...
Autores principales: | Van Gennip, J. L. M., Boswell, C. W., Ciruna, B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291318/ https://www.ncbi.nlm.nih.gov/pubmed/30547092 http://dx.doi.org/10.1126/sciadv.aav1781 |
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