Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells

Anti-tumor mAbs are the most widely used and characterized cancer immunotherapy. Despite having a significant impact on some malignancies, most cancer patients respond poorly or develop resistance to this therapy. A known mechanism of action of these therapeutic mAbs is antibody-dependent cell-media...

Descripción completa

Detalles Bibliográficos
Autores principales: Snyder, Kristin M., Hullsiek, Robert, Mishra, Hemant K., Mendez, Daniel C., Li, Yunfang, Rogich, Allison, Kaufman, Dan S., Wu, Jianming, Walcheck, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291448/
https://www.ncbi.nlm.nih.gov/pubmed/30574146
http://dx.doi.org/10.3389/fimmu.2018.02873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291448/
https://www.ncbi.nlm.nih.gov/pubmed/30574146
http://dx.doi.org/10.3389/fimmu.2018.02873

Ejemplares similares