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Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells

Anti-tumor mAbs are the most widely used and characterized cancer immunotherapy. Despite having a significant impact on some malignancies, most cancer patients respond poorly or develop resistance to this therapy. A known mechanism of action of these therapeutic mAbs is antibody-dependent cell-media...

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Detalles Bibliográficos
Autores principales:	Snyder, Kristin M., Hullsiek, Robert, Mishra, Hemant K., Mendez, Daniel C., Li, Yunfang, Rogich, Allison, Kaufman, Dan S., Wu, Jianming, Walcheck, Bruce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291448/ https://www.ncbi.nlm.nih.gov/pubmed/30574146 http://dx.doi.org/10.3389/fimmu.2018.02873

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