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Site-specific chelator-antibody conjugation for PET and SPECT imaging with radiometals

Antibodies and their derivatives radiolabelled with positron- and gamma-emitting radiometals enable sensitive and quantitative molecular Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) imaging of antibody distribution in vivo. Chelators that are covalently a...

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Detalles Bibliográficos
Autores principales: Morais, Mauricio, Ma, Michelle T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291455/
https://www.ncbi.nlm.nih.gov/pubmed/30553525
http://dx.doi.org/10.1016/j.ddtec.2018.10.002