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Cross-Reactivity of Virus-Specific CD8+ T Cells Against Allogeneic HLA-C: Possible Implications for Pregnancy Outcome

Heterologous immunity of virus-specific T cells poses a potential barrier to transplantation tolerance. Cross-reactivity to HLA-A and -B molecules has broadly been described, whereas responses to allo-HLA-C have remained ill defined. In contrast to the transplant setting, HLA-C is the only polymorph...

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Detalles Bibliográficos
Autores principales: van der Zwan, Anita, van der Meer-Prins, Ellen M. W., van Miert, Paula P. M. C., van den Heuvel, Heleen, Anholts, Jacqueline D. H., Roelen, Dave L., Claas, Frans H. J., Heidt, Sebastiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291497/
https://www.ncbi.nlm.nih.gov/pubmed/30574149
http://dx.doi.org/10.3389/fimmu.2018.02880