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Cross-Reactivity of Virus-Specific CD8+ T Cells Against Allogeneic HLA-C: Possible Implications for Pregnancy Outcome
Heterologous immunity of virus-specific T cells poses a potential barrier to transplantation tolerance. Cross-reactivity to HLA-A and -B molecules has broadly been described, whereas responses to allo-HLA-C have remained ill defined. In contrast to the transplant setting, HLA-C is the only polymorph...
Autores principales: | van der Zwan, Anita, van der Meer-Prins, Ellen M. W., van Miert, Paula P. M. C., van den Heuvel, Heleen, Anholts, Jacqueline D. H., Roelen, Dave L., Claas, Frans H. J., Heidt, Sebastiaan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291497/ https://www.ncbi.nlm.nih.gov/pubmed/30574149 http://dx.doi.org/10.3389/fimmu.2018.02880 |
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