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A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons

Oxysterol analogs that modulate NMDA receptor function are candidates for therapeutic development to treat neuropsychiatric disorders. However, the cellular actions of these compounds are still unclear. For instance, how these compounds are compartmentalized or trafficked in neurons is unknown. In t...

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Detalles Bibliográficos
Autores principales: Chen, Daniel M., Ziolkowski, Luke, Benz, Ann, Qian, Mingxing, Zorumski, Charles F., Covey, Douglas F., Mennerick, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291516/
https://www.ncbi.nlm.nih.gov/pubmed/30574068
http://dx.doi.org/10.3389/fnins.2018.00923