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A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons
Oxysterol analogs that modulate NMDA receptor function are candidates for therapeutic development to treat neuropsychiatric disorders. However, the cellular actions of these compounds are still unclear. For instance, how these compounds are compartmentalized or trafficked in neurons is unknown. In t...
Autores principales: | Chen, Daniel M., Ziolkowski, Luke, Benz, Ann, Qian, Mingxing, Zorumski, Charles F., Covey, Douglas F., Mennerick, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291516/ https://www.ncbi.nlm.nih.gov/pubmed/30574068 http://dx.doi.org/10.3389/fnins.2018.00923 |
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