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Contact Challenge of Cattle with Foot-and-Mouth Disease Virus Validates the Role of the Nasopharyngeal Epithelium as the Site of Primary and Persistent Infection

The pathogenesis of foot-and-mouth disease virus (FMDV) in cattle was investigated through early and late stages of infection by use of an optimized experimental model for controlled contact exposure. Time-limited exposure of cattle to FMDV-infected pigs led to primary FMDV infection of the nasophar...

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Detalles Bibliográficos
Autores principales: Stenfeldt, Carolina, Hartwig, Ethan J., Smoliga, George R., Palinski, Rachel, Silva, Ediane B., Bertram, Miranda R., Fish, Ian H., Pauszek, Steven J., Arzt, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291620/
https://www.ncbi.nlm.nih.gov/pubmed/30541776
http://dx.doi.org/10.1128/mSphere.00493-18