Pharmacokinetics of sodium thiosulfate in Guinea pig perilymph following middle ear application

HYPOTHESIS: To determine the pharmacokinetics of sodium thiosulfate in the inner ear perilymph following middle ear application in Guinea pigs. BACKGROUND: Cisplatin chemotherapy is often associated with a dose-dependent high frequency sensorineural hearing loss. Sodium thiosulfate has been shown to...

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Detalles Bibliográficos
Autores principales: Schroeder, Ronald J., Audlin, Jason, Luo, Juntao, Nicholas, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese PLA General Hospital 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291635/
https://www.ncbi.nlm.nih.gov/pubmed/30559765
http://dx.doi.org/10.1016/j.joto.2017.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291635/
https://www.ncbi.nlm.nih.gov/pubmed/30559765
http://dx.doi.org/10.1016/j.joto.2017.12.001

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