Pioneering topological methods for network-based drug–target prediction by exploiting a brain-network self-organization theory

The bipartite network representation of the drug–target interactions (DTIs) in a biosystem enhances understanding of the drugs’ multifaceted action modes, suggests therapeutic switching for approved drugs and unveils possible side effects. As experimental testing of DTIs is costly and time-consuming...

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Detalles Bibliográficos
Autores principales: Durán, Claudio, Daminelli, Simone, Thomas, Josephine M, Haupt, V Joachim, Schroeder, Michael, Cannistraci, Carlo Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291778/
https://www.ncbi.nlm.nih.gov/pubmed/28453640
http://dx.doi.org/10.1093/bib/bbx041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291778/
https://www.ncbi.nlm.nih.gov/pubmed/28453640
http://dx.doi.org/10.1093/bib/bbx041

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