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Pioneering topological methods for network-based drug–target prediction by exploiting a brain-network self-organization theory
The bipartite network representation of the drug–target interactions (DTIs) in a biosystem enhances understanding of the drugs’ multifaceted action modes, suggests therapeutic switching for approved drugs and unveils possible side effects. As experimental testing of DTIs is costly and time-consuming...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291778/ https://www.ncbi.nlm.nih.gov/pubmed/28453640 http://dx.doi.org/10.1093/bib/bbx041 |