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Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer

BACKGROUND: The transcription factor Snail2 is a repressor of E-cadherin expression during carcinogenesis; however, the specific mechanisms involved in this process in human colorectal cancer (CRC) remain largely unknown. METHOD: We checked the expression of Snail2 in several clinical CRC specimens....

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Detalles Bibliográficos
Autores principales: Hu, Yue, Dai, Mingrui, Zheng, Yayuan, Wu, Jiaxin, Yu, Bin, Zhang, Haihong, Kong, Wei, Wu, Hui, Yu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291922/
https://www.ncbi.nlm.nih.gov/pubmed/30541610
http://dx.doi.org/10.1186/s13148-018-0592-y