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Choroid plexus genes for CSF production and brain homeostasis are altered in Alzheimer’s disease

BACKGROUND: The roles of the choroid plexus (CP) and cerebrospinal fluid (CSF) production have drawn increasing attention in Alzheimer’s disease (AD) research. Specifically, studies document markedly decreased CSF production and turnover in moderate-to-severe AD. Moreover, reduced CP function and CS...

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Detalles Bibliográficos
Autores principales: Kant, Shawn, Stopa, Edward G., Johanson, Conrad E., Baird, Andrew, Silverberg, Gerald D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291926/
https://www.ncbi.nlm.nih.gov/pubmed/30541599
http://dx.doi.org/10.1186/s12987-018-0120-7