Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells

BACKGROUND: Aldehyde dehydrogenase 1A1 (ALDH1A1), a member of aldehyde dehydrogenase family, is a marker of stemness in breast cancer. During tumor progression cancer stem cells (CSCs) have been reported to secrete angiogenic factors to orchestrate the formation of pathological angiogenesis. This va...

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Detalles Bibliográficos
Autores principales: Ciccone, Valerio, Terzuoli, Erika, Donnini, Sandra, Giachetti, Antonio, Morbidelli, Lucia, Ziche, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291966/
https://www.ncbi.nlm.nih.gov/pubmed/30541574
http://dx.doi.org/10.1186/s13046-018-0975-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291966/
https://www.ncbi.nlm.nih.gov/pubmed/30541574
http://dx.doi.org/10.1186/s13046-018-0975-0

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