1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis

BACKGROUND: Tumor cell mediated immune-suppression remains a question of interest in tumor biology. In this study, we focused on the metabolites that are released by prostate cancer cells (PCC), which could potentially attenuate T cell immunity. METHODS: Prostate cancer cells (PCC) media (PCM) was u...

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Detalles Bibliográficos
Autores principales: Yan, Yutao, Chang, Lei, Tian, Hongzhe, Wang, Lu, Zhang, Yawei, Yang, Tao, Li, Guohao, Hu, Weifeng, Shah, Kavita, Chen, Gang, Guo, Yonglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291986/
https://www.ncbi.nlm.nih.gov/pubmed/30545412
http://dx.doi.org/10.1186/s40425-018-0466-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291986/
https://www.ncbi.nlm.nih.gov/pubmed/30545412
http://dx.doi.org/10.1186/s40425-018-0466-z

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