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Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin

Mesenchymal stem cells (MSCs) transfer healthy mitochondria to damaged acceptor cells via actin-based intercellular structures. In this study, we tested the hypothesis that MSCs transfer mitochondria to neural stem cells (NSCs) to protect NSCs against the neurotoxic effects of cisplatin treatment. O...

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Detalles Bibliográficos
Autores principales: Boukelmoune, Nabila, Chiu, Gabriel S., Kavelaars, Annemieke, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292021/
https://www.ncbi.nlm.nih.gov/pubmed/30541620
http://dx.doi.org/10.1186/s40478-018-0644-8