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The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells

BACKGROUND: Millions of people are affected with retinal diseases that eventually cause blindness, and retinal progenitor cell (RPC) transplantation is a promising therapeutic avenue. However, RPC expansion and the underlying regulation mechanisms remain elusive. METHODS: Adult mouse neural RPCs (mN...

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Detalles Bibliográficos
Autores principales: Jin, Caixia, Ou, Qingjian, Li, Zongyi, Wang, Juan, Zhang, Jieping, Tian, Haibin, Xu, Jing-Ying, Gao, Furong, Lu, Lixia, Xu, Guo-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292077/
https://www.ncbi.nlm.nih.gov/pubmed/30545413
http://dx.doi.org/10.1186/s13287-018-1091-y