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The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells
BACKGROUND: Millions of people are affected with retinal diseases that eventually cause blindness, and retinal progenitor cell (RPC) transplantation is a promising therapeutic avenue. However, RPC expansion and the underlying regulation mechanisms remain elusive. METHODS: Adult mouse neural RPCs (mN...
Autores principales: | Jin, Caixia, Ou, Qingjian, Li, Zongyi, Wang, Juan, Zhang, Jieping, Tian, Haibin, Xu, Jing-Ying, Gao, Furong, Lu, Lixia, Xu, Guo-Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292077/ https://www.ncbi.nlm.nih.gov/pubmed/30545413 http://dx.doi.org/10.1186/s13287-018-1091-y |
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