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A statistical framework for detecting mislabeled and contaminated samples using shallow-depth sequence data
BACKGROUND: Researchers typically sequence a given individual multiple times, either re-sequencing the same DNA sample (technical replication) or sequencing different DNA samples collected on the same individual (biological replication) or both. Before merging the data from these replicate sequence...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292093/ https://www.ncbi.nlm.nih.gov/pubmed/30541436 http://dx.doi.org/10.1186/s12859-018-2512-8 |