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Colony-stimulating factor 1 receptor inhibition prevents disruption of the blood-retina barrier during chronic inflammation

BACKGROUND: Microglia-associated inflammation is closely related to the pathogenesis of various retinal diseases such as uveitis and diabetic retinopathy, which are associated with increased vascular permeability. In this study, we investigated the effect of systemic lipopolysaccharide (LPS) exposur...

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Detalles Bibliográficos
Autores principales: Kokona, Despina, Ebneter, Andreas, Escher, Pascal, Zinkernagel, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292111/
https://www.ncbi.nlm.nih.gov/pubmed/30541565
http://dx.doi.org/10.1186/s12974-018-1373-4