The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

BACKGROUND: The continued spectre of resistance to existing anti-malarials necessitates the pursuit of novel targets and mechanisms of action for drug development. One class of promising targets consists of the 80S ribosome and its associated components comprising the parasite translational apparatu...

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Detalles Bibliográficos
Autores principales: Sheridan, Christine Moore, Garcia, Valentina E., Ahyong, Vida, DeRisi, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292128/
https://www.ncbi.nlm.nih.gov/pubmed/30541569
http://dx.doi.org/10.1186/s12936-018-2616-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292128/
https://www.ncbi.nlm.nih.gov/pubmed/30541569
http://dx.doi.org/10.1186/s12936-018-2616-7

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