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Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression

BACKGROUND: The tetraspanins Tspan8 and CD151 promote metastasis, exosomes (Exo) being suggested to be important in the crosstalk between tumor and host. The contribution of Tspan8 and CD151 to host versus tumor-derived exosome (TEX) activities being not defined, we approached the questions using 3-...

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Detalles Bibliográficos
Autores principales: Zhao, Kun, Wang, Zhe, Hackert, Thilo, Pitzer, Claudia, Zöller, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292129/
https://www.ncbi.nlm.nih.gov/pubmed/30541597
http://dx.doi.org/10.1186/s13046-018-0961-6