miR-29 Family Inhibits Resistance to Methotrexate and Promotes Cell Apoptosis by Targeting COL3A1 and MCL1 in Osteosarcoma

BACKGROUND: MicroRNAs (miRNAs) play a crucial role in regulating diverse biological processes, including drug resistance. We investigated the potential roles of the miR-29 family in methotrexate (MTX) resistance in osteosarcoma. MATERIAL/METHODS: Two MTX-resistant osteosarcoma cell lines, MG-63/MTX...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Li, Zhikun, Zhu, Xiaodong, Xu, Ruijun, Xu, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292150/
https://www.ncbi.nlm.nih.gov/pubmed/30518744
http://dx.doi.org/10.12659/MSM.911972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292150/
https://www.ncbi.nlm.nih.gov/pubmed/30518744
http://dx.doi.org/10.12659/MSM.911972

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