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miR-29 Family Inhibits Resistance to Methotrexate and Promotes Cell Apoptosis by Targeting COL3A1 and MCL1 in Osteosarcoma

BACKGROUND: MicroRNAs (miRNAs) play a crucial role in regulating diverse biological processes, including drug resistance. We investigated the potential roles of the miR-29 family in methotrexate (MTX) resistance in osteosarcoma. MATERIAL/METHODS: Two MTX-resistant osteosarcoma cell lines, MG-63/MTX...

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Detalles Bibliográficos
Autores principales:	Xu, Wei, Li, Zhikun, Zhu, Xiaodong, Xu, Ruijun, Xu, Youjia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292150/ https://www.ncbi.nlm.nih.gov/pubmed/30518744 http://dx.doi.org/10.12659/MSM.911972

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