Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication

BACKGROUND: Ligands for the Toll-like receptor (TLR) family can induce activation of cells of the innate immune system and are widely studied for their potential to enhance adaptive immunity. Conjugation of TLR2-ligand Pam3CSK4 to synthetic long peptides (SLPs) was shown to strongly enhance the indu...

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Detalles Bibliográficos
Autores principales: Zom, Gijs G., Willems, Marian M. J. H. P., Khan, Selina, van der Sluis, Tetje C., Kleinovink, Jan Willem, Camps, Marcel G. M., van der Marel, Gijsbert A., Filippov, Dmitri V., Melief, Cornelis J. M., Ossendorp, Ferry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292168/
https://www.ncbi.nlm.nih.gov/pubmed/30541631
http://dx.doi.org/10.1186/s40425-018-0455-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292168/
https://www.ncbi.nlm.nih.gov/pubmed/30541631
http://dx.doi.org/10.1186/s40425-018-0455-2

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