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Pilot trial of inosine to elevate urate levels in amyotrophic lateral sclerosis
OBJECTIVE: To test the safety, tolerability, and urate‐elevating capability of the urate precursor inosine taken orally or by feeding tube in people with amyotrophic lateral sclerosis (ALS). METHODS: This was a pilot, open‐label trial in 25 participants with ALS. Treatment duration was 12 weeks. The...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292193/ https://www.ncbi.nlm.nih.gov/pubmed/30564619 http://dx.doi.org/10.1002/acn3.671 |