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ADAR1 silencing-induced HUVEC apoptosis is mediated by FGFR2 under hypoxia stress
BACKGROUND: The adenosine deaminase acting on RNA 1 (ADAR1) specifically deaminates adenosine to inosine in double-stranded RNA (dsRNA). Emerging evidence indicated that under hypoxia condition, such as tumor microenvironment, ADAR1 level was increased. Interestingly, we found FGFR2 was also increas...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292393/ https://www.ncbi.nlm.nih.gov/pubmed/30573948 http://dx.doi.org/10.2147/DDDT.S181312 |