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Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) RNAi is associated with cell cycle inhibition, apoptosis, DNA damage response and drug sensitivity in breast cancer

Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) is an important susceptibility locus for nicotine addiction and lung cancer. Depletion of CHRNA5 has been associated with reduced cell viability, increased apoptosis and alterations in cellular motility in different cancers yet not in breast cancer. He...

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Detalles Bibliográficos
Autores principales: Cingir Koker, Sahika, Jahja, Ermira, Shehwana, Huma, Keskus, Ayse Gokce, Konu, Ozlen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292578/
https://www.ncbi.nlm.nih.gov/pubmed/30543688
http://dx.doi.org/10.1371/journal.pone.0208982