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Organic barn dust inhibits surfactant protein D production through protein kinase-c alpha dependent increase of GPR116

Prolonged exposure to organic barn dusts can lead to chronic inflammation and a broad range of lung problems over time, mediated by innate immune mechanisms. The immune surfactant or collectin surfactant protein D (SP-D) is a crucial multifunctional innate immune receptor. Little work to date has ex...

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Detalles Bibliográficos
Autores principales: Schneberger, David, DeVasure, Jane M., Kirychuk, Shelley A., Wyatt, Todd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292596/
https://www.ncbi.nlm.nih.gov/pubmed/30543664
http://dx.doi.org/10.1371/journal.pone.0208597