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Organic barn dust inhibits surfactant protein D production through protein kinase-c alpha dependent increase of GPR116
Prolonged exposure to organic barn dusts can lead to chronic inflammation and a broad range of lung problems over time, mediated by innate immune mechanisms. The immune surfactant or collectin surfactant protein D (SP-D) is a crucial multifunctional innate immune receptor. Little work to date has ex...
Autores principales: | Schneberger, David, DeVasure, Jane M., Kirychuk, Shelley A., Wyatt, Todd A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292596/ https://www.ncbi.nlm.nih.gov/pubmed/30543664 http://dx.doi.org/10.1371/journal.pone.0208597 |
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