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A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children’s Oncology Group study

This study explores the genomic alterations that contribute to the formation of a unique subset of low-risk, epithelial differentiated, favorable histology Wilms tumors (WT), tumors that have been characterized by their expression of post-induction renal developmental genes (Subset 1 WT). We demonst...

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Detalles Bibliográficos
Autores principales: Armstrong, Amy E., Gadd, Samantha, Huff, Vicki, Gerhard, Daniela S., Dome, Jeffrey S., Perlman, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292605/
https://www.ncbi.nlm.nih.gov/pubmed/30543698
http://dx.doi.org/10.1371/journal.pone.0208936