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LbL-assembled gentamicin delivery system for PMMA bone cements to prolong antimicrobial activity

INTRODUCTION: Antibiotic-loaded poly(methyl methacrylate) bone cements (ALBCs) are widely used in total joint replacement (TJR), for local delivery of antibiotics to provide prophylaxis against prosthetic joint infections (PJI). One of the shortcomings of the current generation of ALBCs is that the...

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Detalles Bibliográficos
Autores principales: Al Thaher, Yazan, Yang, Lirong, Jones, Steve A., Perni, Stefano, Prokopovich, Polina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292632/
https://www.ncbi.nlm.nih.gov/pubmed/30543660
http://dx.doi.org/10.1371/journal.pone.0207753