Chain organization of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci

We investigate spatiotemporal dynamics of human interphase chromosomes by employing a heteropolymer model that incorporates the information of human chromosomes inferred from Hi-C data. Despite considerable heterogeneities in the chromosome structures generated from our model, chromatins are organiz...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Shi, Guang, Thirumalai, D., Hyeon, Changbong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292649/
https://www.ncbi.nlm.nih.gov/pubmed/30507936
http://dx.doi.org/10.1371/journal.pcbi.1006617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292649/
https://www.ncbi.nlm.nih.gov/pubmed/30507936
http://dx.doi.org/10.1371/journal.pcbi.1006617

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