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Chain organization of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci
We investigate spatiotemporal dynamics of human interphase chromosomes by employing a heteropolymer model that incorporates the information of human chromosomes inferred from Hi-C data. Despite considerable heterogeneities in the chromosome structures generated from our model, chromatins are organiz...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292649/ https://www.ncbi.nlm.nih.gov/pubmed/30507936 http://dx.doi.org/10.1371/journal.pcbi.1006617 |