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A comprehensive ensemble model for comparing the allosteric effect of ordered and disordered proteins
Intrinsically disordered proteins/regions (IDPs/IDRs) are prevalent in allosteric regulation. It was previously thought that intrinsic disorder is favorable for maximizing the allosteric coupling. Here, we propose a comprehensive ensemble model to compare the roles of both order-order transition and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292653/ https://www.ncbi.nlm.nih.gov/pubmed/30507941 http://dx.doi.org/10.1371/journal.pcbi.1006393 |