Cargando…

Hydroxynorketamine: Implications for the NMDA Receptor Hypothesis of Ketamine’s Antidepressant Action

The prevailing hypothesis of ketamine’s unique antidepressant effects implicates N-methyl-d-aspartate receptor (NMDAR) inhibition-dependent enhancement of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated transmission, activation of intracellular signalling pathways and increase...

Descripción completa

Detalles Bibliográficos
Autores principales: Aleksandrova, Lily R., Wang, Yu Tian, Phillips, Anthony G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292673/
https://www.ncbi.nlm.nih.gov/pubmed/30556028
http://dx.doi.org/10.1177/2470547017743511